Ashwagandha and Reishi Mushroom Benefits: A Blend for Reducing Stress†

Stress is an unavoidable part of our modern life, and finding ways to manage it can help us navigate daily stressors. Stress management techniques you may have learned about from stress relief trends, like mindfulness and meditation, are a great start, and clinically studied adaptogens like Nature Made’s ashwagandha and reishi mushroom blend can support a daily calm routine.^†

Ashwagandha and reishi mushrooms are adaptogens, which are compounds found in specific plants or mushrooms that work gently over time to help the body adapt to stressors.^[1] Let’s explore the benefits of the ashwagandha and reishi mushroom blend, how it was studied, timing details, and the best way to work Nature Made^® Ashwagandha + Reishi Mushroom Capsules into your daily routine.

Why Combine Ashwagandha and Reishi Mushrooms?

You might see supplements containing either of these ingredients alone and wonder why they are combined. Well, did you know that both ashwagandha and reishi mushroom are adaptogens? An adaptogen is a type of substance, usually an herb, root or mushroom, that helps the body adapt to stressors over time, which is why these two ingredients were blended and clinically studied. Nature Made Ashwagandha + Reishi Mushroom benefits include helping reduce stress while supporting calm, relaxation, and a healthy mood.^†

A double-blind, placebo-controlled study was conducted with a group of nearly 500 adult participants to measure the effects of an ashwagandha and reishi mushroom blend on perceived stress. After 6 weeks, people who took an ashwagandha + reishi blend daily reported feeling less stressed.^[2]

This blend of ashwagandha + reishi mushroom is included in our Ashwagandha + Reishi Mushroom Capsules due to its adaptogenic properties that help the body adapt to stressors without being a stimulant or a sedative, supporting an improved mood, and supporting relief from occasional anxiousness when taken consistently.^†

Supporting calm and relaxation is a lifelong journey, and supplementation from a trusted brand is a convenient way to add a little calm into your daily routine. Each two-capsule serving of this stress support supplement, contains a blend 600 mg of KSM-66^® ashwagandha and 400 mg of reishi mushroom fruiting body extract to help reduce stress. Consider adding our ashwagandha and reishi supplement to your daily routine.^†

Explore: Ashwagandha Supplements

Ashwagandha Benefits for Stress and Mood

What are ashwagandha benefits for stress and mood? Our ashwagandha + reishi mushroom blend includes KSM-66^® Ashwagandha, a concentrated, standardized root extract that has been clinically studied for its stress-reducing effects.^†

Ashwagandha is an adaptogen that supports a healthy stress response and helps reduce stress. It also helps reduce the stress hormone cortisol. An ashwagandha supplement provides daily support for stress and occasional anxiousness and helps support a healthy mood.^†

Ashwagandha has a long history, as it has been revered in Ayurvedic medicine as an adaptogenic herb that supports stress resilience.^[3] Today it is recognized through clinical studies for its ability to help reduce stress. Nature Made’s Ashwagandha + Reishi Capsules provide 600 mg of KSM-66^® Ashwagandha per daily 2-capsule serving, clinically studied to help reduce stress.^†

When to Take Ashwagandha and Reishi

Adding an ashwagandha + reishi stress support supplement to your routine is simple; there's no reason to add another stressor to your plate! The first thing you want to do is give the label a good look-over. The label will include important information, such as serving size, daily dosage, and suggested use instructions, helping you understand and use your supplement.

The suggested use for Nature Made’s Ashwagandha + Reishi Capsules is to take 2 capsules daily with water. Consistency is key, and one of the best ways to support daily consistency is to link your calm supplement routine to a regular daily meal, so you take it at the same time every day. Adaptogens for stress work gently over time, helping your body adapt to stressors with daily use, so keeping a consistent daily routine is important.

In as little as 6 weeks, people who took this clinically studied blend daily felt noticeably less stressed.^[2] If you are pregnant, attempting to become pregnant, nursing, taking any medications, or have any chronic medical conditions, consult your physician before use. Consulting a trusted healthcare practitioner before adding any supplement to your daily routine is a great first step for personalized advice and recommendations to help you reach your unique health goals.^†

How Nature Made Ashwagandha + Reishi Supports Daily Calm

Take a step toward supporting your daily calm with Nature Made Ashwagandha + Reishi Mushroom Capsules. Our convenient daily supplement includes a clinically studied adaptogenic blend of ashwagandha and reishi mushroom extracts to help reduce stress, and support calm, relaxation, and a healthy mood.^†

Nature Made prides itself on supplements with high-quality ingredients, and this supplement is no exception. KSM-66^® Ashwagandha is sourced from roots and standardized for potency, so you get the same dose of active ingredient in every serving to help reduce levels of the stress hormone cortisol. Similarly, reishi mushroom (Ganoderma lingzhi) extract is derived from the fruiting body and standardized to 35% beta-glucans.^†

For adults looking for a clinically studied, non-habit-forming option to help manage daily stress and support calm, Nature Made Ashwagandha + Reishi Capsules can be a convenient way to work daily stress support into a well-rounded wellness routine, and complement stress management activities like meditation and mindfulness. Nature Made is the #1 Pharmacist-Recommended Vitamin & Supplement Brand.*

KSM-66^® is a registered trademark of Ixoreal Biomed Inc.

* Based on a survey of pharmacists who recommend branded vitamins and supplements

References:

1. Cleveland Clinic. What are Adaptogens & Types. Cleveland Clinic. Published February 10, 2022. https://my.clevelandclinic.org/health/drugs/22361-adaptogens
2. Gundermann D, Ghatak S, Wilcox ML, Maki KC, Pauli EK. A Randomized, Double-Blind, Placebo-Controlled Study to Investigate the Effects of a Reishi Mushroom and Ashwagandha Supplement on Perceived Stress in Healthy Adults. Current Developments in Nutrition. 2025;9:106183. doi:https://doi.org/10.1016/j.cdnut.2025.106183
3. National Center for Complementary and Integrative Health. Ashwagandha. NCCIH. Published March 2023. https://www.nccih.nih.gov/health/ashwagandha